LONDON (Reuters) – The UK medical regulator has said no one with a history of anaphylaxis to a drug or food should be vaccinated against the Pfizer-BioTech Covit-19 vaccine, which provides complete guidance on early allergy warnings about the shot. The Pfizer / Bioendech Covit-19 vaccine was administered at a vaccination center in Japan on the first day of the largest immunization program in British history, on December 8, 2020 in Cardiff, Wales, UK. Started, which is part of a global drive, one of the biggest logistics challenges in peacetime history. The Pharmaceutical and Health Products Regulatory Agency (MHRA) had two reports on anaphylaxis and one on an allergic reaction since the start of the rollout. “Anyone with a history of anaphylaxis for a vaccine, drug or diet should not receive the Pfi zer BioNTech vaccine,” MHRA CEO Jun Raine said in a statement. Strong standards of safety, quality and performance. “Anaphylaxis is an overgrowth of the body’s immune system, which the National Health Service describes as severe and sometimes life-threatening. The full guidance makes it clear that the main risk is from anaphylaxis in particular. After consulting allergists. The MHRA initially advised not to take a shot at anyone with a history of “significant allergic reaction”. Pfizer and Bioendech said they support the MHRA’s investigation. Last week, the world’s first to approve the UK’s MHRA vaccine, developed by Germany’s Bioendech and Pfizer, followed by data from the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). Evaluate. Americans with severe U.S. allergic reactions should not be Pfizer’s Govt candidates, he said Wednesday. -19 Vaccine until you understand more about what happened. The Canadian Ministry of Health said it was looking into the adverse reactions reported in the UK, but said adverse events should be expected and would not change the risk / benefit of the shot. The country approved the vaccine. He told lawmakers that such allergic reactions were not a feature of Pfizer’s clinical trials. Those with Pfizer vaccines or the candidate’s history of severe adverse allergic reactions were excluded from their subsequent stage trials, which reflected the MHRA’s emergency approval protocol. However, allergic reactions may have been caused by a component of Pfizer’s vaccine, known as polyethylene glycol, or P And not in other types of vaccines. Paul Turner of Imperial College London, an expert in the field of allergies and immunology, told Reuters, who advised MHRA in the revised guideline: “With as much information as we have, the initial concern that affects everyone with allergies is not true. ”“ Products like PEG, which we think may cause reactions, are not related to things that cause food allergies. Similarly, people with known allergies to a drug should not be at risk, ”Turner told Reuters. The EMA said in an email that all quality, safety and efficacy data would be taken into account in evaluating the vaccine, and that the FDA released documents on Tuesday in preparation for an advisory panel meeting at the EU on Thursday, including data generated outside, to meet its expectations for the effectiveness and safety data recognition of the Pfizer vaccine. . Summary Documents 0.63% of people in the immunization group and 0.51% of the placebo group recorded allergic reactions to trials, which Peter Peter Obshaw, a professor of experimental medicine at Imperial College London, said was the lowest number. “As soon as we know about these two allergic reactions, the regulator has taken this step to provide precautionary advice, which shows that the monitoring system is working better,” he said. However, Gregory Poland, a virologist and vaccine researcher at the Mayo Clinic in Rochester, Minnesota, said the MHRA and NHS were initially exaggerated. “I would not have expanded as much as they did,” he said. “It is only fair that the world should be made aware of this and that there are people who have such reactions to vaccines. I think drugs, foods or any other allergies are beyond the scope of science. ”Alistair Smout Report; Additional report by Josephine Mason, Ludwig Burger, Francesco Curacio and Julie Steinhusen; Editing by Paul Sandil, Alexandra Hudson, Gareth Jones and Cynthia Asterman.
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