Tough months are ahead, but the release of the first vaccine at the time of registration and the immediate approval of others is a turning point for rich countries that can afford to buy the vaccine. Rich countries have been involved in a vaccine shopping industry for months. The continuously updated database compiled by the Duke Global Health Innovation Center shows billions of dollars worth of bilateral agreements by a few countries for emerging vaccines. Many countries and territories have pre-determined vaccines that are larger than their entire population. The People’s Vaccine Coalition, an international vaccination watchdog that includes Amnesty International and Oxfam, said last week that rich countries had purchased enough Govt-19 vaccine doses to prevent their population from tripled. Citizens are five or six times more likely, however, not all vaccine candidates recommended by it will be approved for use. Coalition data show that while the world’s richest nations are breaking contracts, nearly 70 poor countries will be able to vaccinate only one in 10 people by 2021. “Despite the goal of equality around the world, it is disappointing. Vaccine nationalism is so high,” said Gregory Hussey, a professor at the University of Cape Town who is on the cabinet committee to advise the South African government on access to the Govt-19 vaccine. Speaking to CNN on Thursday, John Nkenkasong, head of the Centers for Disease Control and Prevention in Africa, said the inability of poor countries to access vaccines was a “disaster.” “This is the moment when we all talk about global solidarity and global cooperation. The litmus test is really just now. It is not entirely moral to say that some countries have high doses of vaccines, while others do not have the same amount of vaccines as parts of the world,” he said. As hospitals filled, there seemed to be a global effort to get everyone finally vaccinated. Called the Compact Kovacs and led by the vaccine alliance Kavi. It runs on two tracks. High- and middle-income countries have provided substantial funding to ensure equal access to vaccines and vaccine production. Poor countries, mostly on the African continent, have signed up with a separate Kovacs facility to protect against vaccines. These vaccines will be funded by donations from development agencies and groups such as the Bill & Melinda Gates Foundation. So far, 189 countries and territories have signed up to these two facilities. Neither the United States nor Russia. Last week, Dr. Anthony Fossie, the United States’ top epidemiologist, said in his personal capacity that his country had a “moral obligation” to ensure that the Covit-19 vaccine was distributed fairly. Called for. Eligible access to vaccines is not just a matter of money. A spokesman for Kavi said the coalition had raised more than $ 2 billion to buy vaccines for poorer countries and needed to raise more than $ 5 billion by the end of next year. “Our priority is to get the funding we need to get quick access to these countries. For Covit-19 vaccine candidates through the Kovacs facility,” the spokesman told CNN, but the money cannot buy vaccines already sold. Kovacs’ major contributors, such as the European Union, the United Kingdom and Canada, have large-scale bilateral agreements with pharmaceutical companies. The People’s Vaccine Coalition argues that these deals could undermine the Kovacs agreement they funded. In fact, Canada is one of the largest donors to the Kovacs project, which allows equal access to poor countries. In an interview on Friday, Canadian International Development Minister Karina Gold said her country needs to defend its challenges because most vaccines are still in development and therefore only in theory. “Like the Kovacs facility, we have contracts with many vaccine companies that recognize that not all of these vaccines will be successful,” he said, adding that the government is committed to equality and affordable access to vaccines. “We are not a country isolated from the world. We have friends and family and business partners in every region of the world. Canadians can be vaccinated and keep them safe, but we do not want to be cut off from the world,” Gold said. Dr Richard Mihingo, the World Health Organization (WHO) coordinator for immunization and vaccination development in the African region, said he understood the need for countries to ensure their citizens are vaccinated. He called the bilateral agreements “tragic truth.” “Raising money is one thing, gaining access to the product is another. Without supply there is not enough funding. This complicates the situation,” he said. The WHO’s goal is to vaccinate 20% of the population in the African region by the end of 2020, but more meaningful protection could take two to three years. Mihingo believes the public health risks will be exacerbated by the spread of the virus in regions that fail to get a vaccine. Bitter Memories Scientists still remember years of dental and nail fights over access to life-saving drugs to fight HIV / AIDS in the West, even after African public health officials found it. Most recently, despite similar talk of similarity, the H1N1 flu vaccine came to the continent in 2009 after an epidemic peak. Hussey hopes the Govt-19 vaccine debate will refresh these painful memories. “This is not a new phenomenon. It has manifested itself many times in the past,” he said. There are numerous historical and contemporary examples of life-saving drugs being available to the rich but not to the poor. If unity cannot be defeated by moral argument, the authorities of the continent hope that the public health argument will do so. Stamping Govt-19 everywhere is an epidemiological requirement. “As long as everyone is protected, no one can be safe. We live in an interconnected world, and even if those countries can protect themselves, they will live on an island. We need a world with which we can communicate, not only socially, but also economically,” Mihingo said. He believes the long-term impact of any vaccine recession in poor countries will widen global inequalities. Mihingo said the vaccine passport will be required for travel, study and trade as rich countries vaccinate their citizens. This has already been tested by the Australian airline Qantas. This would be a way to lock down developing countries while opening up other parts of the world. “It reminds me of the old racist days when a black African needed a pass to get out of his ghetto and into the city. The notion that no one backed down was a lot Baltardash at the end of the day,” said Hussey, a professor at the University of Cape Town. A window to get it right Despite the intense pressures on vaccine supply, Kovacs’ goal is to deliver nearly 1 billion vaccines to low-income countries by the end of 2021. Public health officials who spoke with CNN believe that rich countries will change their unused orders in COVAX. Gold said those guarantees were too quick, but the Canadian government is actively discussing with Kovacs what a donation mechanism would look like. Although vaccines are shared, not all of them are suitable for low-income countries. Pfizer / Bioentech and Modern vaccines are expensive and require intensive cold storage, which is a challenge for countries with low health infrastructure. Chinese synoform vaccine efficacy data have not yet been publicly shared, but Chinese officials are strongly pushing it as a viable solution for low-income countries. Johnson & Johnson has entered into an agreement with South African pharmaceutical company Aspen Pharmacare to manufacture its vaccine, with no guarantee that those quantities will go to the continent. The most promising initial solution for low-income countries is the Oxford University / AstroGeneca vaccine, the only one to date that has been reviewed for its effectiveness and safety. The vaccine can be carried out using basic refrigeration and the 1 billion vaccines will be manufactured by Serum Company in India and will be distributed to poor countries by COVAX at production cost. In addition to that confirmation, billions of Oxford vaccine drugs already exist have been confirmed elsewhere by bilateral agreements. Mihingo says the next few months will be crucial to ensure that most of the world’s population does not lag behind in the greatest vaccine drive of our time. They not only save the lives of the most vulnerable, but also open up business opportunities and help lift themselves out of poverty, ”he said.
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