(Adds details from British regulator) December 9 (Reuters) – The UK drug regulator has advised people with significant allergic history not to receive the Pfizer-Bioentech Covit-19 vaccine. Here are some questions and answers about the cases, what they mean is that anaphylaxis can cause sore throat, respiratory distress and difficulty swallowing, according to the American Academy of Allergy, Asthma & Immunology. Anaphylaxis is an overactive reaction of the body’s immune system, which the UK National Health Service describes as severe and sometimes life-threatening. Together with UK regulators, who should not be vaccinated? Anyone with a remarkable history said that the British regulators initially responded. Do not take a shot at an allergic reaction to a vaccine, medication or food. The group’s adviser later said that part of saying there was no risk of food allergies was “twisting.” Late on Wednesday, the UK regulator said no one with a history of anaphylaxis should receive a vaccine, medication or diet. Vaccine. Pfizer had a significant adverse reaction to the vaccine or its vaccine products were excluded from the late phase trials. How are these useful programs for US recognition? U.S. regulators are expected to consider the emergency approval of the Pfizer vaccine as soon as Thursday. Meeting of consultants. Manshef Slavy, who is leading the US government’s vaccine development efforts, said on Wednesday that he expects British allergic reactions to be considered in the US accreditation process and that those with more severe allergic reactions should not take the vaccine too much. Understood. What do doctors say? The story goes that some praised the UK regulators’ warning, while others said broad controls were not needed b available evidence. “For the general public, this does not mean they should be worried about getting vaccinated,” said Stephen Evans, a professor of pharmacology at the London School of Hygiene and Tropical Medicine. What would be wise is that “anyone who knows of a severe allergic reaction should take epipheny to delay vaccination until the cause of the allergic reaction is clarified,” he said. Mayo Clinic virologist Gregory Poland, who advised U.S. regulators, described Britain’s initial reaction as “exaggerating it”, pointing to the initial response to food allergies, which he said had “nothing to do with it”. “I said,‘ If there are anaphylactic level reactions to vaccines, we want to know about it, so we pay extra attention, ’” he said. “That doesn’t mean I won’t give you immunity, but I will do it in a very controlled setting.” Peter Openshaw, professor of experimental medicine at Imperial College London, praised the way the reactions were handled. “The fact that we are quickly aware of these two allergic reactions and that the regulator has acted to provide precautionary advice shows that the monitoring system is performing better,” he said. The nationwide Children’s Hospital in Ohio has expressed concern about how this issue could dampen interest in vaccines. “I’m worried that millions of people will choose not to be vaccinated because the whole event is heard,” he said. How common are severe or significant allergies? “There were seven hospital admissions in the UK in 2012 for 100,000 people with severe allergies. This includes different stimuli such as foods, drugs and insect bites,” said Louisa James, an immunologist at Queen Mary University in London. Deaths are very rare and have not increased even as hospital admissions have increased in many countries. (Reported by Kate Kelland and Alistair Smout in London, Julie Steinhussen in Chicago, and Michael Herman in New Jersey and Carl O’Donnell in New York; Editing by Peter Henderson, Tom Brown and Leslie Adler)
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